Symptoms Of Overdose Of Vitamin A And ESymptoms Of Overdose Of Vitamin A And E
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Symptoms Of Overdose Of Vitamins A And E

As both vitamin A and vitamin E are fat-soluble vitamins but disposing of any excesses taken in through diet is much harder than with water-soluble vitamins like vitamins B and C.

  

As such, vitamin A overdose can result in:  

  1. This can lead to nausea, jaundice, irritability, decreased sensation of appetite, vomiting, blurry vision, headaches, muscle and abdominal pain and weakness, drowsiness and altered mental status. Acute toxicity generally occurs at doses of 7500 µg daily for 6-15 months. Children can reach toxic levels at 450 µg.
  2. However, liver toxicities can occur at levels as low as 4,500µg per day
  3. In people with renal failure 1200 µg can cause substantial damage.
  4. In chronic cases, hair loss, drying of the mucous membranes, fever, insomnia, fatigue, weight loss, bone fractures, anemia, and diarrhea can all be evident on top of the symptoms associated with less serious toxicity.
  5. Intake of twice the RDA of preformed vitamin A chronically may be associated with osteoporosis and hip fractures.
  6. Toxic effects have been shown to Therapeutic doses of vitamin A used for acne treatment have been shown to significantly affect developing fetuses..
  7. Chronically high doses of Vitamin A can produce the syndrome of "pseudotumor cerebri". This syndrome includes headache, blurring of vision and confusion.
        Overdose of vitamin E toxicity may interfere with vitamin K action and enhance the effect of some anticoagulant drugs. As vitamin E foods are fat soluble, even high amounts of vitamin E cannot be taken without increasing the cholesterol intake, leading to higher chances of cardio-vascular diseases. A meta-analysis that combined the results of 19 clinical trials of vitamin E supplementation for various diseases, including heart diseases, reported that the increased risk of death was associated with a level of 1330mg per day.

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Symptoms Of Overdose Of Vitamin A And E

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